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  • 产品名称：TumorNecrosisFactorReceptorSuperfamily,Member11a,NFKBActivator(TNFRSF11A)(Activ

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  • 产品厂商：SXBIO
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简单介绍：
TumorNecrosisFactorReceptorSuperfamily,Member11a,NFKBActivator(TNFRSF11A)(Active)Protein
详情介绍：
Sequence QIAPPCTSEK HYEHLGRCCN KCEPGKYMSS KCTTTSDSVC LPCGPDEYLD SWNEEDKCLL HKVCDTGKAL VAVVAGNSTT PRRCACTAGY HWSQDCECCR RNTECAPGLG AQHPLQLNKD TVCKPCLAGY FSDAFSSTDK CRPWTNCTFL GKRVEHHGTE KSDAVCSSSL PARK
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit sRANK Ligand induced nuclear factor kappa B(NFkappaB) in RAW 264.7 cells is less than 50 ng/mL, corresponding to a specific activity of ＞ 2.0 x 104 IU/mg
Purity >98 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Receptor for TNFSF11/RANKL/TRANCE/OPGL, essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. {ECO:0000269|PubMed:9878548}.
Synonyms: Osteoclast differentiation factor receptor, Receptor activator of NF-KB, CD antigen CD265
Molecular Weight 19.1 kDa
UniProt Q9Y6Q6
Pathways NF-kappaB Signaling
Restrictions For Research Use only
Format Lyophilized
Buffer 20 mM Tris-HCl, pH 8.0, 150 mM NaCl
Storage -20 °C