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  • 产品名称：FibroblastGrowthFactor4(FGF4)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
FibroblastGrowthFactor4(FGF4)(Active)Protein
详情介绍：
Sequence GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 ng/mL, corresponding to a specific activity of ＞ 2.0 x 106 IU/mg.
Purity >96 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal limb and cardiac valve development during embryogenesis. {ECO:0000269|PubMed:8663044}.
Synonyms: FGF-4, HST, HST-1, HSTF-1, Heparin-binding growth factor 4
Molecular Weight 19.8 kDa
UniProt P08620
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance
Restrictions For Research Use only
Format Lyophilized
Buffer PBS, pH 7.4, 300 mM NaCl
Storage -20 °C