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  • 产品名称：ThymicStromalLymphopoietin(TSLP)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
ThymicStromalLymphopoietin(TSLP)(Active)Protein
详情介绍：
Sequence MYDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPT AGCASLAKEM FAMKTKAALA IWCPGYSETQ INATQAMKKR RKRKVTTNKC LEQVSQLQGL WRRFNRPLLK QQ
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human IL-7Rα and human TSLP R co-transfected murine BaF3 pro-B cells is less than 0.3 ng/mL, corresponding to a specific activity of ＞ 3.3 x 10
Purity >98 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. {ECO:0000269|PubMed:11418668, ECO:0000269|PubMed:11480573, ECO:0000269|PubMed:17242164}., Isoform 2: May act as an antimicrobial peptide in the oral cavity and on the skin. {ECO:0000269|PubMed:24850429}.
Molecular Weight 15.1 kDa
UniProt Q969D9
Research Area Immunology, Innate Immunity, Cytokines
Restrictions For Research Use only
Format Lyophilized
Buffer 20 mM PB, pH 7.4, 150 mM NaCl
Storage -20 °C