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  • 产品名称：MHCClassIPolypeptide-RelatedSequenceB(MICB)(Active)Protein

  • 产品型号：
  • 产品厂商：SXBIO
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简单介绍：
MHCClassIPolypeptide-RelatedSequenceB(MICB)(Active)Protein
详情介绍：
Sequence AEPHSLRYNL MVLSQDESVQ SGFLAEGHLD GQPFLRYDRQ KRRAKPQGQW AEDVLGAKTW DTETEDLTEN GQDLRRTLTH IKDQKGGLHS LQEIRVCEIH EDSSTRGSRH FYYDGELFLS QNLETQESTV PQSSRAQTLA MNVTNFWKED AMKTKTHYRA MQADCLQKLQ RYLKSGVAIR RTVPPMVNVT CSEVSEGNIT VTCRASSFYP RNITLTWRQD GVSLSHNTQQ WGDVLPDGNG TYQTWVATRI RQGEEQRFTC YMEHSGNHGT HPVPSGKVLV LQSQRTD
Characteristics Biological Activity: Fully biologically active when compared to standard. The specific activity is determined by binding MICB antibody in ELISA.
Purity >95 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. {ECO:0000269|PubMed:11491531, ECO:0000269|PubMed:11777960, ECO:0000269|PubMed:9497295}.
Synonyms: MIC-B,
Molecular Weight 32.8 kDa
UniProt Q29980
Restrictions For Research Use only
Format Lyophilized
Buffer 20 mM Tris, 150 mM NaCl, pH 8.0
Storage -20 °C