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  • 产品名称：anti-Agouti-Related(AA83-132)antibody

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  • 产品厂商：SXBIO
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简单介绍：
anti-Agouti-Related(AA83-132)antibody
详情介绍：
Immunogen Recombinant human Agouti-related protein(83-132AA)
Isotype IgG
Purification Caprylic Acid Ammonium Sulfate Precipitation purified
Background Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
UniProt O00253
Restrictions For Research Use only
Format Liquid
Buffer Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C