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Background
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Relevance: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. Synonyms: IL-2, TCGF, Aldesleukin
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Molecular Weight
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15.4 kDa
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UniProt
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P60568
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Research Area
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Immunology, Innate Immunity, Cytokines
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Pathways
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JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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