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  • 产品名称：FibroblastGrowthFactor1(Acidic)(FGF1)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
FibroblastGrowthFactor1(Acidic)(FGF1)(Active)Protein
详情介绍：
Sequence MAEGEITTFT ALTEKFNLPP GNYKKPKLLY CSNGGHFLRI LPDGTVDGTR DRSDQHIQLQ LSAESVGEVY IKSTETGQYL AMDTDGLLYG SQTPNEECLF LERLEENHYN TYISKKHAEK NWFVGLKKNG SCKRGPRTHY GQKAILFLPL PVSSD
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 0.5 ng/mL, corresponding to a specific activity of ＞ 2.0 x 106 IU/mg in the presence of 10 μg/mL of hepari
Purity >97 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. {ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:20145243, ECO:0000269|PubMed:8663044}.
Synonyms: FGF-1, aFGF, Endothelial cell growth factor, ECGF, Heparin-binding growth factor 1
Molecular Weight 17.5 kDa
UniProt P05230
Research Area Cancer, Angiogenesis, Growth Factors
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Restrictions For Research Use only
Format Lyophilized
Buffer PBS, pH 7.4, with 2 mM EDTA, 0.5 mM DTT, 5 % Trehalose
Storage -20 °C