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  • 产品名称:anti-AminoacyltRNASynthaseComplexInteractingMultifunctionalProtein1(AA25-180)an

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简单介绍:
anti-AminoacyltRNASynthaseComplexInteractingMultifunctionalProtein1(AA25-180)antibody
详情介绍:
Immunogen Recombinant human Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 protein(25-180aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name Aminoacyl tRNA Synthase Complex-Interacting Multifunctional Protein 1
Background Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
UniProt Q12904
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C