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  • 产品名称：NerveGrowthFactorbeta(NGFB)(AA122-241)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
NerveGrowthFactorbeta(NGFB)(AA122-241)(Active)Protein
详情介绍：
Sequence Ser122-Ala241, Accession # CAA36832
Characteristics Biological Activity: The ED50, as determined by a cell proliferation assay using human TF-1 cells, is less than 2 ng/mL.
Purity >90 % as determined by SDS-PAGE.
Sterility 0.2 μm filtered
Background Relevance: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177). {ECO:0000269|PubMed:20164177}.
Synonyms: Beta-NGF,
Molecular Weight 13.5 kDa
UniProt P01138
Research Area Neurology, Growth Factors
Pathways NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size
Restrictions For Research Use only
Format Lyophilized
Buffer 0.2 % acetic acid
Storage -20 °C