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  • 产品名称：anti-MTM1antibody(Myotubularin1)(AA484-603)

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  • 产品厂商：SXBIO
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简单介绍：
anti-MTM1antibody(Myotubularin1)(AA484-603)
详情介绍：
Immunogen Recombinant human Myotubularin protein (484-603aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name Myotubularin (MTM1 Antibody Abstract)
Background Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.
UniProt Q13496
Pathways Inositol Metabolic Process, Skeletal Muscle Fiber Development
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C