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  • 产品名称：anti-CCAR1antibody(CellDivisionCycleandApoptosisRegulator1)(AA1-200)

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  • 产品厂商：SXBIO
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简单介绍：
anti-CCAR1antibody(CellDivisionCycleandApoptosisRegulator1)(AA1-200)
详情介绍：
Immunogen Recombinant human Cell division cycle and apoptosis regulator protein 1 protein (1-200aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name Cell Division Cycle and Apoptosis Regulator Protein 1 (CCAR1 Antibody Abstract)
Background Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.
UniProt Q8IX12
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C