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  • 产品名称：anti-TumorNecrosisFactor(Ligand)Superfamily,Member18(TNFSF18)(AA72-199)antibody

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  • 产品厂商：SXBIO
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简单介绍：
anti-TumorNecrosisFactor(Ligand)Superfamily,Member18(TNFSF18)(AA72-199)antibody
详情介绍：
Immunogen Recombinant human Tumor necrosis factor ligand superfamily member 18 protein (72-199aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name Tumor Necrosis Factor Ligand Superfamily Member 18 (TNFSF18 Antibody Abstract)
Background Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation.
UniProt Q9UNG2
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C