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  • 产品名称：anti-TIRAPantibody(Toll-Interleukin1Receptor(TIR)DomainContainingAdaptorProtein

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  • 产品厂商：SXBIO
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简单介绍：
anti-TIRAPantibody(Toll-Interleukin1Receptor(TIR)DomainContainingAdaptorProtein)(AA1-221)
详情介绍：
Immunogen Recombinant human Toll/interleukin-1 receptor domain-containing adapter protein (1-221aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name Toll/interleukin-1 Receptor Domain-Containing Adapter Protein (TIRAP Antibody Abstract)
Background Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.
UniProt P58753
Pathways TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C