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  • 产品名称：anti-CD22antibody(CD22Molecule)(AA708-847)

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  • 产品厂商：SXBIO
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简单介绍：
anti-CD22antibody(CD22Molecule)(AA708-847)
详情介绍：
Immunogen Recombinant human B-cell receptor CD22 protein(708-847aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name B-Cell Receptor CD22 (CD22 Antibody Abstract)
Background Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
UniProt P20273
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C