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  • 产品名称：anti-FADDantibody(Fas(TNFRSF6)-AssociatedViaDeathDomain)(AA1-208)

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  • 产品厂商：SXBIO
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简单介绍：
anti-FADDantibody(Fas(TNFRSF6)-AssociatedViaDeathDomain)(AA1-208)
详情介绍：
Immunogen Recombinant human FAS-associated death domain protein(1-208aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name FAS-Associated Death Domain Protein (FADD Antibody Abstract)
Background Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
UniProt Q13158
Pathways Apoptosis, TLR Signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C