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  • 产品名称：anti-CytoplasmicProteinNCK1antibody(NCKAdaptorProtein1)(AA58-377)

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  • 产品厂商：SXBIO
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简单介绍：
anti-CytoplasmicProteinNCK1antibody(NCKAdaptorProtein1)(AA58-377)
详情介绍：
Immunogen Recombinant human Cytoplasmic protein NCK1 protein(58-377aa)
Isotype IgG
Purification Antigen Affinity purified
Alternative Name Cytoplasmic Protein NCK1 (NCK1 Antibody Abstract)
Background Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors.
UniProt P16333
Pathways TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C