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  • 产品名称：anti-NR2C1antibody(NuclearReceptorSubfamily2,GroupC,Member1)(AA1-240)

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  • 产品厂商：SXBIO
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简单介绍：
anti-NR2C1antibody(NuclearReceptorSubfamily2,GroupC,Member1)(AA1-240)
详情介绍：
Immunogen Recombinant human Nuclear receptor subfamily 2 group C member 1 protein(1-240aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name Nuclear Receptor Subfamily 2 Group C Member 1 (NR2C1 Antibody Abstract)
Background Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.
UniProt P13056
Pathways Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C