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  • 产品名称：anti-aHSPantibody(alphaHemoglobinStabilizingProtein)

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简单介绍：
anti-aHSPantibody(alphaHemoglobinStabilizingProtein)
详情介绍：
Immunogen Anti-AHSP Antibody was produced from whole rabbit serum prepared by repeated immunizations with the full length human AHSP protein.
Immunogen Type: RecombinantProtein
Specificity Anti-AHSP Antibody is directed against the human AHSP protein. The product was prepared from monospecific antiserum by delipidation and defibrination. A BLAST analysis was used to suggest cross reactivity with human and mouse. Cross-reactivity with AHSP from other sources have not been determined.
Characteristics AHSP Antibody detects Alpha hemoglobin stabilizing protein (AHSP). AHSP acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. AHSP binds free a-globin to promote its folding and inhibit its ability to produce damaging reactive oxygen species. Reduced AHSP levels correlate with increased severity of b-thalassemia in some human cohorts.
Sterility Sterile filtered
Alternative Name AHSP (aHSP Antibody Abstract)
Background AHSP Antibody detects Alpha hemoglobin stabilizing protein (AHSP). AHSP acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. AHSP binds free a-globin to promote its folding and inhibit its ability to produce damaging reactive oxygen species. Reduced AHSP levels correlate with increased severity of b-thalassemia in some human cohorts.
Synonyms: Alpha-hemoglobin-stabilizing protein (AHSP), Erythroid differentiation-related factor, Erythroid-associated factor, EDRF, ERAF
Gene ID 51327
NCBI Accession NP_057717
UniProt Q9NZD4
Application Notes Anti-AHSP Antibody is suitable for western blotting, immunohistochemistry (Formalin-fixed paraffin-embedded sections), immunofluorescence microscopy using paraformaldehyde-fixed primary cardiomyocyte cultures and ELISA. Researchers should determine optimal titers for applications that are not stated below.
Comment

Gene Name: AHSP
Restrictions For Research Use only
Format Liquid
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
Expiry Date 12 months
Supplier Images
Immunohistochemistry (IHC) image for anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (ABIN1043696) Immunohistochemistry of Rabbit anti-AHSP antibody. Tissue: A. Normal bone marrow, H&E...
image for anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (ABIN1043696) anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (Image 2)
image for anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (ABIN1043696) anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (Image 3)
image for anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (ABIN1043696) anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (Image 4)
image for anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (ABIN1043696) anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (Image 5)
image for anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (ABIN1043696) anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (Image 6)
image for anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (ABIN1043696) anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (Image 7)
image for anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (ABIN1043696) anti-alpha Hemoglobin Stabilizing Protein (aHSP) antibody (Image 8)
Product cited in: Nasimuzzaman, Khandros, Wang, Kong, Zhao, Weiss, Rivella, Weiss, Persons: "Analysis of alpha hemoglobin stabilizing protein overexpression in murine β-thalassemia." in: American journal of hematology, Vol. 85, Issue 10, pp. 820-2, 2010 (PubMed).