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  • 产品名称:anti-DARCantibody(DuffyBloodGroup,ChemokineReceptor)(AA1-30)

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简单介绍:
anti-DARCantibody(DuffyBloodGroup,ChemokineReceptor)(AA1-30)
详情介绍:
Immunogen This DARC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DARC.
Clone RB42735
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name DARC (DARC Antibody Abstract)
Background The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms: DARC, FY, GPD, Duffy antigen/chemokine receptor, Fy glycoprotein, Glycoprotein D, Plasmodium vivax receptor, CD_antigen=CD234
NCBI Accession NP_001116423, NP_002027
UniProt Q16570
Research Area Signaling, Innate Immunity, Chemokines
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Duffy Blood Group, Chemokine Receptor (DARC) (AA 1-30), (N-Term) antibody (ABIN1881251) DARC Antibody (N-term) (ABIN1881251) western blot analysis in CEM cell line lysates (...
Product cited in: Silva, Blanton, Parrado, Melo, Morato, Reis, Dias, Castro, Vasconcelos, Goddard, Barreto, Reis, Teixeira: "Dengue hemorrhagic fever is associated with polymorphisms in JAK1." in: European journal of human genetics : EJHG, Vol. 18, Issue 11, pp. 1221-7, 2010 (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Le Goff, Brès, Rigal, Blum, Marquette: "Robust, high-throughput solution for blood group genotyping." in: Analytical chemistry, Vol. 82, Issue 14, pp. 6185-92, 2010 (PubMed).

Di Cristofaro, Silvy, Chiaroni, Bailly: "Single PCR multiplex SNaPshot reaction for detection of eleven blood group nucleotide polymorphisms: optimization, validation, and one year of routine clinical use." in: The Journal of molecular diagnostics : JMD, Vol. 12, Issue 4, pp. 453-60, 2010 (PubMed).