产品详情
所在位置: 首页> 产品目录> 一抗>
查看大图

  • 产品名称：anti-GUCA1Bantibody(GuanylateCyclaseActivator1B(Retina))(AA29-57)

  • 产品型号：
  • 产品厂商：半导体
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
anti-GUCA1Bantibody(GuanylateCyclaseActivator1B(Retina))(AA29-57)
详情介绍：
Immunogen This GUCA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human GUCA1B.
Clone RB40485
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name GUCA1B (GUCA1B Antibody Abstract)
Background The protein encoded by this gene is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa. [provided by RefSeq].

Synonyms: GUCA1B, GCAP2, Guanylyl cyclase-activating protein 2, Guanylate cyclase activator 1B
NCBI Accession NP_002089
UniProt Q9UMX6
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Guanylate Cyclase Activator 1B (Retina) (GUCA1B) (AA 29-57), (N-Term) antibody (ABIN1881399) GUCA1B Antibody (N-term) (ABIN1881399) western blot analysis in A549 cell line lysate...
Product cited in: Sato, Nakazawa, Usui, Tanimoto, Abe, Ohguro: "Mutations in the gene coding for guanylate cyclase-activating protein 2 (GUCA1B gene) in patients with autosomal dominant retinal dystrophies." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 243, Issue 3, pp. 235-42, 2005 (PubMed).

Nishiguchi, Sokal, Yang, Roychowdhury, Palczewski, Berson, Dryja, Baehr: "A novel mutation (I143NT) in guanylate cyclase-activating protein 1 (GCAP1) associated with autosomal dominant cone degeneration." in: Investigative ophthalmology & visual science, Vol. 45, Issue 11, pp. 3863-70, 2004 (PubMed).

Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003 (PubMed).