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  • 产品名称：anti-EOMESantibody(Eomesodermin)(AA28-57)

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简单介绍：
anti-EOMESantibody(Eomesodermin)(AA28-57)
详情介绍：
Immunogen This EOMES antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-57 amino acids from the N-terminal region of human EOMES.
Clone RB40942
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name EOMES (EOMES Antibody Abstract)
Background This gene encodes a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation.

Synonyms: EOMES, TBR2, Eomesodermin homolog, T-box brain protein 2
NCBI Accession NP_005433, NP_001265111, NP_001265112
UniProt O95936
Pathways Stem Cell Maintenance
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Eomesodermin (EOMES) (AA 28-57), (N-Term) antibody (ABIN1881298) EOMES Antibody (N-term) (ABIN1881298) western blot analysis in A375 cell line lysates...
Product cited in: Wang, Ge, Xue, Li: "[Role of transcription factor T-bet and Eomes in IFN-gamma secretion of different human T cell subsets]." in: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, Vol. 26, Issue 1, pp. 31-4, 2010 (PubMed).

Sessa, Mao, Hadjantonakis, Klein, Broccoli: "Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex." in: Neuron, Vol. 60, Issue 1, pp. 56-69, 2008 (PubMed).

Background publications Araki, Fann, Wersto, Weng: "Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: perforin and granzyme B)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 12, pp. 8102-8, 2008 (PubMed).