anti-Syntaxin7(STX7)(AA47-73),(N-Term)antibody 抗体网

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产品名称：anti-Syntaxin7(STX7)(AA47-73),(N-Term)antibody
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产品厂商：半导体
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简单介绍：

anti-Syntaxin7(STX7)(AA47-73),(N-Term)antibody

详情介绍：

Product details
Product details
Immunogen	This STX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-73 amino acids from the N-terminal region of human STX7.
Clone	RB21640
Predicted Reactivity	Cow (Bovine),Mouse (Murine),Rat (Rattus)
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Target details
Target details
Alternative Name	STX7 (STX7 Antibody Abstract)
Background	Syntaxin 7 is involved in the ordered fusion of endosomes and lysosomes with the phagosome, where phagocytic cells kill and degrade internalized foreign particles. Syntaxin 7 is found in late endosomes and lysosomes, whereas Syntaxin 12 is localized to the recycling endosome compartment, both are recruited to the phagosome. However, STX12 is acquired earlier before rapidly recycling off the phagosome, whereas STX7 is recruited later and continues to accumulate throughout the phagosome maturation process. Synonyms: STX7, Syntaxin-7
NCBI Accession	NP_003560
UniProt	O15400
Pathways	Synaptic Vesicle Exocytosis

Application Details
Application Details
Application Notes	WB: 1:1000,IHC (p): 1:50-100,FACS: 1:10-50
Restrictions	For Research Use only

Handling
Handling
Format	Liquid
Concentration	0.5 mg/mL
Buffer	Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative	Sodium azide
Precaution of Use	WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Images
Images
Supplier Images	STX7 Antibody (N-term) (ABIN1881855) flow cytometric analysis of MDA-MB231 cells (rig... STX7 Antibody (N-term) (ABIN1881855) flow cytometric analysis of MDA-MB231 cells (rig... STX7 Antibody (N-term) (ABIN1881855) flow cytometric analysis of MDA-MB231 cells (rig... Images for product: anti-Syntaxin 7 (STX7) (AA 47-73), (N-Term) antibody STX7 Antibody (N-term) (ABIN1881855) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. STX7 Antibody (N-term) (ABIN1881855) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. STX7 Antibody (N-term) (ABIN1881855) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

References
References
Background publications	Prekeris, Yang, Oorschot, Klumperman, Scheller: "Differential roles of syntaxin 7 and syntaxin 8 in endosomal trafficking." in: Molecular biology of the cell, Vol. 10, Issue 11, pp. 3891-908, 1999 (PubMed). Wong, Xu, Zhang, Hong: "Syntaxin 7, a novel syntaxin member associated with the early endosomal compartment." in: The Journal of biological chemistry, Vol. 273, Issue 1, pp. 375-80, 1998 (PubMed).
Product cited in:	Steegmaier, Yang, Yoo, Huang, Shen, Yu, Luo, Scheller: "Three novel proteins of the syntaxin/SNAP-25 family." in: The Journal of biological chemistry, Vol. 273, Issue 51, pp. 34171-9, 1999 (PubMed).