anti-tauTubulinKinase1(Ttbk1)(AA230-258),(N-Term)antibody 抗体网

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产品名称：anti-tauTubulinKinase1(Ttbk1)(AA230-258),(N-Term)antibody
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产品厂商：半导体
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简单介绍：

anti-tauTubulinKinase1(Ttbk1)(AA230-258),(N-Term)antibody

详情介绍：

Product details
Product details
Immunogen	This TTBK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-258 amino acids from the N-terminal region of human TTBK1.
Clone	RB24987
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Target details
Target details
Alternative Name	TTBK1 (Ttbk1 Antibody Abstract)
Background	TTBK1 is Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU. Synonyms: TTBK1, BDTK, KIAA1855, Tau-tubulin kinase 1, Brain-derived tau kinase
NCBI Accession	NP_115927
UniProt	Q5TCY1

Application Details
Application Details
Application Notes	WB: 1:1000,IHC (p): 1:50-100
Restrictions	For Research Use only

Handling
Handling
Format	Liquid
Concentration	0.5 mg/mL
Buffer	Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative	Sodium azide
Precaution of Use	WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Images
Images
Supplier Images	TTBK1 Antibody (N-term) (ABIN1881955) IHC analysis in formalin fixed and paraffin emb... TTBK1 Antibody (N-term) (ABIN1881955) IHC analysis in formalin fixed and paraffin emb... Images for product: anti-tau Tubulin Kinase 1 (Ttbk1) (AA 230-258), (N-Term) antibody TTBK1 Antibody (N-term) (ABIN1881955) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TTBK1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. TTBK1 Antibody (N-term) (ABIN1881955) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TTBK1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

References
References
Product cited in:	Sato, Xu, Okuyama, Martinez, Walsh, Jacobsen, Swan, Schlautman, Ciborowski, Ikezu: "Spatial learning impairment, enhanced CDK5/p35 activity, and downregulation of NMDA receptor expression in transgenic mice expressing tau-tubulin kinase 1." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 53, pp. 14511-21, 2009 (PubMed).