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  • 产品名称：anti-ICAM-1antibody(IntercellularAdhesionMolecule1)(AA488-514)

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简单介绍：
anti-ICAM-1antibody(IntercellularAdhesionMolecule1)(AA488-514)
详情介绍：
Immunogen This ICAM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 488-514 amino acids from the C-terminal region of human ICAM1.
Clone RB20472
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name ICAM1 (ICAM1 Antibody Abstract)
Background ICAM1 is a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.

Synonyms: ICAM1, Intercellular adhesion molecule 1, Major group rhinovirus receptor, CD_antigen=CD54, Flags: Precursor
NCBI Accession NP_000192
UniProt P05362
Pathways Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
Application Notes WB: 1:1000,FACS: 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Flow Cytometry (FACS) image for anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 488-514), (C-Term) antibody (ABIN1882096) ICAM1 Antibody (C-term) (ABIN1882096) flow cytometric analysis of k562 cells (bottom ...
Western Blotting (WB) image for anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 488-514), (C-Term) antibody (ABIN1882096) ICAM1 Antibody (C-term) (ABIN1882096) flow cytometric analysis of k562 cells (bottom ...
Product cited in: Fang, Yang, Yuan, Gao, Zhou, Chen, Xu: "Myocardin-related transcription factor A mediates OxLDL-induced endothelial injury." in: Circulation research, Vol. 108, Issue 7, pp. 797-807, 2011 (PubMed).

Denkers, de Jong-de Boer, Beelen, Ossenkoppele, Langenhuijsen: "VLA molecule expression may be involved in the release of acute myeloid leukaemic cells from the bone marrow." in: Leukemia research, Vol. 16, Issue 5, pp. 469-74, 1992 (PubMed).

Rössler, Neuchrist, Kitz, Scheiner, Kraft, Lassmann: "Expression of leucocyte adhesion molecules at the human blood-brain barrier (BBB)." in: Journal of neuroscience research, Vol. 31, Issue 2, pp. 365-74, 1992 (PubMed).