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  • 产品名称:anti-RXFP1antibody(Relaxin/insulin-LikeFamilyPeptideReceptor1)(AA685-713)

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简单介绍:
anti-RXFP1antibody(Relaxin/insulin-LikeFamilyPeptideReceptor1)(AA685-713)
详情介绍:
Immunogen This RXFP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 685-713 amino acids from the C-terminal region of human RXFP1.
Clone RB41815
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name RXFP1 (RXFP1 Antibody Abstract)
Background Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.

Synonyms: RXFP1, LGR7, Relaxin receptor 1, Leucine-rich repeat-containing G-protein coupled receptor 7, Relaxin family peptide receptor 1
NCBI Accession NP_067647, NP_001240658, NP_001240657
UniProt Q9HBX9
Pathways Myometrial Relaxation and Contraction
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Relaxin/insulin-Like Family Peptide Receptor 1 (RXFP1) (AA 685-713), (C-Term) antibody (ABIN1881770) RXFP1 Antibody (C-term) (ABIN1881770) western blot analysis in A375 cell line lysates...
Product cited in: Halls, Cooper: "Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex." in: The EMBO journal, Vol. 29, Issue 16, pp. 2772-87, 2010 (PubMed).