产品详情
所在位置: 首页> 产品目录> 一抗>
查看大图

  • 产品名称：anti-LGALS3BPantibody(Lectin,Galactoside-Binding,Soluble,3BindingProtein)(AA383

  • 产品型号：
  • 产品厂商：半导体
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
anti-LGALS3BPantibody(Lectin,Galactoside-Binding,Soluble,3BindingProtein)(AA383-412)
详情介绍：
Immunogen This LGALS3BP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-412 amino acids from the Central region of human LGALS3BP.
Clone RB40516
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name LGALS3BP (LGALS3BP Antibody Abstract)
Background The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.

Synonyms: LGALS3BP, M2BP, Galectin-3-binding protein, Basement membrane autoantigen p105, Lectin galactoside-binding soluble 3-binding protein, Mac-2-binding protein, Tumor-associated antigen 90K
NCBI Accession NP_005558
UniProt Q08380
Research Area Cancer, Cell Cycle
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.45 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Lectin, Galactoside-Binding, Soluble, 3 Binding Protein (LGALS3BP) (AA 383-412), (Center) antibody (ABIN1881492) LGALS3BP Antibody (Center) (ABIN1881492) western blot analysis in mouse lung tissue l...
Product cited in: Srirajaskanthan, Caplin, Waugh, Watkins, Meyer, Hsuan, Beaumont: "Identification of Mac-2-binding protein as a putative marker of neuroendocrine tumors from the analysis of cell line secretomes." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 4, pp. 656-66, 2010 (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Zambelli, Zuntini, Nardi, Manara, Serra, Landuzzi, Lollini, Ferrari, Alberghini, Llombart-Bosch, Piccolo, Iacobelli, Picci, Scotlandi: "Biological indicators of prognosis in Ewing's sarcoma: an emerging role for lectin galactoside-binding soluble 3 binding protein (LGALS3BP)." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 1, pp. 41-52, 2009 (PubMed).

Lee, Zhang, Shin, Lee, Kim: "Mac-2 binding protein and galectin-3 expression in mucinous tumours of the ovary: an annealing control primer system and immunohistochemical study." in: Pathology, Vol. 41, Issue 3, pp. 229-33, 2009 (PubMed).

Kim, Lee, Sung, Choi, Choi, Kim, Kim, Yu, Hwang, Kim: "Increased serum 90K and Galectin-3 expression are associated with advanced stage and a worse prognosis in diffuse large B-cell lymphomas." in: Acta haematologica, Vol. 120, Issue 4, pp. 211-6, 2009 (PubMed).