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  • 产品名称：anti-CCL17antibody(Chemokine(C-CMotif)Ligand17)(AA65-94)

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  • 产品厂商：半导体
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简单介绍：
anti-CCL17antibody(Chemokine(C-CMotif)Ligand17)(AA65-94)
详情介绍：
Immunogen This CCL17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from the C-terminal region of human CCL17.
Clone RB40883
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name CCL17 (CCL17 Antibody Abstract)
Background This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

Synonyms: CCL17, SCYA17, TARC, C-C motif chemokine 17, CC chemokine TARC, Small-inducible cytokine A17, Thymus and activation-regulated chemokine
NCBI Accession NP_002978
UniProt Q92583
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Chemokine (C-C Motif) Ligand 17 (CCL17) (AA 65-94), (C-Term) antibody (ABIN1881150) CCL17 Antibody (C-term) (ABIN1881150) western blot analysis in NCI-H460 cell line lys...
Product cited in: Dallos, Heiland, Strehl, Karonitsch, Gross, Moosig, Holl-Ulrich, Distler, Manger, Schett, Zwerina: "CCL17/thymus and activation-related chemokine in Churg-Strauss syndrome." in: Arthritis and rheumatism, Vol. 62, Issue 11, pp. 3496-503, 2010 (PubMed).

Maruyama, Kono, Izawa, Mizukami, Kawaguchi, Mimura, Watanabe, Fujii: "CCL17 and CCL22 chemokines within tumor microenvironment are related to infiltration of regulatory T cells in esophageal squamous cell carcinoma." in: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E, Vol. 23, Issue 5, pp. 422-9, 2010 (PubMed).

Schuurhof, Bont, Siezen, Hodemaekers, van Houwelingen, Kimman, Hoebee, Kimpen, Janssen: "Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls." in: Pediatric pulmonology, Vol. 45, Issue 6, pp. 608-13, 2010 (PubMed).

Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).