产品详情
所在位置: 首页> 产品目录> 一抗>
查看大图

  • 产品名称：anti-POU2AF1antibody(POUClass2AssociatingFactor1)

  • 产品型号：
  • 产品厂商：半导体
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
anti-POU2AF1antibody(POUClass2AssociatingFactor1)
详情介绍：
Immunogen Purified His-tagged POU2AF1 protein was used to produced this monoclonal antibody.
Clone 1170CT1-1-1
Isotype IgG1, kappa
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name POU2AF1 (POU2AF1 Antibody Abstract)
Background Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.

Synonyms: POU2AF1,OBF1, POU domain class 2-associating factor 1, POU domain class 2-associating factor 1, B-cell-specific coactivator OBF-1, POU domain class 2-associating factor 1, BOB-1, POU domain class 2-associating factor 1, OCA-B, POU domain class 2-associating factor 1, OCT-binding factor 1
NCBI Accession NP_006226
UniProt Q16633
Application Notes WB: 1:4000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-POU Class 2 Associating Factor 1 (POU2AF1) antibody (ABIN1882276) POU2AF1 Antibody (ABIN1882276) western blot analysis in Daudi cell line lysates (35 µ...
Background publications Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Strubin, Newell, Matthias: "OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins." in: Cell, Vol. 80, Issue 3, pp. 497-506, 1995 (PubMed).

Product cited in: Galiègue-Zouitina, Quief, Hildebrand, Denis, Lecocq, Collyn-dHooghe, Bastard, Yuille, Dyer, Kerckaert: "Fusion of the LAZ3/BCL6 and BOB1/OBF1 genes by t(3; 11) (q27; q23) chromosomal translocation." in: Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie, Vol. 318, Issue 11, pp. 1125-31, 1996 (PubMed).

Luo, Roeder: "Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B." in: Molecular and cellular biology, Vol. 15, Issue 8, pp. 4115-24, 1995 (PubMed).