anti-serpinPeptidaseInhibitor,CladeA(Alpha-1Antiproteinase,Antitrypsin),Member3 抗体网

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产品名称：anti-serpinPeptidaseInhibitor,CladeA(Alpha-1Antiproteinase,Antitrypsin),Member3
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简单介绍：

anti-serpinPeptidaseInhibitor,CladeA(Alpha-1Antiproteinase,Antitrypsin),Member3(SERPINA3)(AA282-310),(C-Term)antibody

详情介绍：

Product details
Product details
Immunogen	This SERPINA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-310 amino acids from the C-terminal region of human SERPINA3.
Clone	RB18483
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)

Target details
Target details
Alternative Name	SERPINA3 (SERPINA3 Antibody Abstract)
Background	SERPINA3 is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. Synonyms: SERPINA3, AACT, Alpha-1-antichymotrypsin, Cell growth-inhibiting gene 24/25 protein, Serpin A3, Alpha-1-antichymotrypsin His-Pro-less
NCBI Accession	NP_001076
UniProt	P01011

Application Details
Application Details
Application Notes	WB: 1:1000,FACS: 1:10-50
Restrictions	For Research Use only

Handling
Handling
Format	Liquid
Concentration	2 mg/mL
Buffer	Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative	Sodium azide
Precaution of Use	WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Images
Images
Supplier Images	SERPINA3 Antibody (C-term) (ABIN1882130) flow cytometry analysis of MDA-MB231 cells (... SERPINA3 Antibody (C-term) (ABIN1882130) flow cytometry analysis of MDA-MB231 cells (... Images for product: anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) (AA 282-310), (C-Term) antibody SERPINA3 Antibody (C-term) (ABIN1882130) flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. SERPINA3 Antibody (C-term) (ABIN1882130) flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

References
References
Product cited in:	Baumann, Huber, Bode, Grosse, Lesjak, Laurell: "Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7 A resolution and its comparison with other serpins." in: Journal of molecular biology, Vol. 218, Issue 3, pp. 595-606, 1991 (PubMed). Abraham, Shirahama, Potter: "Alpha 1-antichymotrypsin is associated solely with amyloid deposits containing the beta-protein. Amyloid and cell localization of alpha 1-antichymotrypsin." in: Neurobiology of aging, Vol. 11, Issue 2, pp. 123-9, 1990 (PubMed).