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  • 产品名称：anti-CNTFantibody(CiliaryNeurotrophicFactor)(AA114-140)

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  • 产品厂商：半导体
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简单介绍：
anti-CNTFantibody(CiliaryNeurotrophicFactor)(AA114-140)
详情介绍：
Immunogen This CNTF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-140 amino acids from the Central region of human CNTF.
Clone RB44449
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name CNTF (CNTF Antibody Abstract)
Background CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.

Synonyms: CNTF,Ciliary neurotrophic factor
NCBI Accession NP_000605
UniProt P26441
Research Area Stem Cells
Pathways JAK-STAT Signaling
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.3 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Ciliary Neurotrophic Factor (CNTF) (AA 114-140), (Center) antibody (ABIN1881219) CNTF Antibody (Center) (ABIN1881219) western blot analysis in U87-MG cell line lysate...
Product cited in: Takahashi, Yokoji, Misawa, Hayashi, Hu, Deguchi: "A null mutation in the human CNTF gene is not causally related to neurological diseases." in: Nature genetics, Vol. 7, Issue 1, pp. 79-84, 1994 (PubMed).

Masiakowski, Liu, Radziejewski, Lottspeich, Oberthuer, Wong, Lindsay, Furth, Panayotatos: "Recombinant human and rat ciliary neurotrophic factors." in: Journal of neurochemistry, Vol. 57, Issue 3, pp. 1003-12, 1991 (PubMed).

Negro, Tolosano, Skaper, Martini, Callegaro, Silengo, Fiorini, Altruda: "Cloning and expression of human ciliary neurotrophic factor." in: European journal of biochemistry / FEBS, Vol. 201, Issue 1, pp. 289-94, 1991 (PubMed).

McDonald, Ko, Mismer, Smith, Collins: "Expression and characterization of recombinant human ciliary neurotrophic factor from Escherichia coli." in: Biochimica et biophysica acta, Vol. 1090, Issue 1, pp. 70-80, 1991 (PubMed).

Lam, Fuller, Miller, Kloss, Manthorpe, Varon, Cordell: "Sequence and structural organization of the human gene encoding ciliary neurotrophic factor." in: Gene, Vol. 102, Issue 2, pp. 271-6, 1991 (PubMed).