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  • 产品名称:anti-ECE2antibody(EndothelinConvertingEnzyme2)(AA551-579)

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简单介绍:
anti-ECE2antibody(EndothelinConvertingEnzyme2)(AA551-579)
详情介绍:
Immunogen This ECE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-579 amino acids from the Central region of human ECE2.
Clone RB43866
Predicted Reactivity Cow (Bovine),Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name ECE2 (ECE2 Antibody Abstract)
Background Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.

Synonyms: ECE2,KIAA0604, Endothelin-converting enzyme 2, Methyltransferase-like region, Endothelin-converting enzyme 2 region
NCBI Accession NP_055508, NP_001093590, NP_001093591, NP_001032401, NP_115707
UniProt O60344
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.31 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Endothelin Converting Enzyme 2 (ECE2) (AA 551-579), (Center) antibody (ABIN1881279) ECE2 Antibody (Center) (ABIN1881279) western blot analysis in U251 cell line lysates ...
Product cited in: Muzny, Scherer, Kaul, Wang, Yu, Sudbrak, Buhay, Chen, Cree, Ding, Dugan-Rocha, Gill, Gunaratne, Harris, Hawes, Hernandez, Hodgson, Hume, Jackson, Khan, Kovar-Smith, Lewis, Lozado, Metzker et al.: "The DNA sequence, annotation and analysis of human chromosome 3. ..." in: Nature, Vol. 440, Issue 7088, pp. 1194-8, 2006 (PubMed).

Lorenzo, Khan, Wang, Tai, Chan, Cheung, Marsden: "Human endothelin converting enzyme-2 (ECE2): characterization of mRNA species and chromosomal localization." in: Biochimica et biophysica acta, Vol. 1522, Issue 1, pp. 46-52, 2001 (PubMed).

Nagase, Ishikawa, Miyajima, Tanaka, Kotani, Nomura, Ohara: "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 5, Issue 1, pp. 31-9, 1998 (PubMed).

Background publications Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).