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  • 产品名称：anti-Granulinantibody(GRN)(AA563-591)

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简单介绍：
anti-Granulinantibody(GRN)(AA563-591)
详情介绍：
Immunogen This GRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 563-591 amino acids from the C-terminal region of human GRN.
Clone RB44397
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name GRN (GRN Antibody Abstract)
Background Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth.

Synonyms: GRN,Granulins, Granulins, Proepithelin, Acrogranin, Paragranulin, Granulin-1, Granulin-1, Granulin G, Granulin-2, Granulin-2, Granulin F, Granulin-3, Granulin-3, Granulin B, Granulin-4, Granulin-4, Granulin A, Granulin-5, Granulin-5, Granulin C, Granulin-6, Granulin-6, Granulin D, Granulin-7, Granulin-7, Granulin E
NCBI Accession NP_002078
UniProt P28799
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Granulin (GRN) (AA 563-591), (C-Term) antibody (ABIN1881391) GRN Antibody (C-term) (ABIN1881391) western blot analysis in A2058,HepG2,HL-60,T47D c...
Product cited in: Bhandari, Bateman: "Structure and chromosomal location of the human granulin gene." in: Biochemical and biophysical research communications, Vol. 188, Issue 1, pp. 57-63, 1992 (PubMed).

Plowman, Green, Neubauer, Buckley, McDonald, Todaro, Shoyab: "The epithelin precursor encodes two proteins with opposing activities on epithelial cell growth." in: The Journal of biological chemistry, Vol. 267, Issue 18, pp. 13073-8, 1992 (PubMed).

Bhandari, Palfree, Bateman: "Isolation and sequence of the granulin precursor cDNA from human bone marrow reveals tandem cysteine-rich granulin domains." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 5, pp. 1715-9, 1992 (PubMed).