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  • 产品名称：anti-TSPY-Like2(TSPYL2)(AA380-409),(Center)antibody

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简单介绍：
anti-TSPY-Like2(TSPYL2)(AA380-409),(Center)antibody
详情介绍：
Immunogen This TSPYL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-409 amino acids from the Central region of human TSPYL2.
Clone RB43626
Predicted Reactivity Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name TSPYL2 (TSPYL2 Antibody Abstract)
Background Part of the CASK/TRB1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.

Synonyms: TSPYL2,CDA1, DENTT, TSPX, Testis-specific Y-encoded-like protein 2, Testis-specific Y-encoded-like protein 2, Cell division autoantigen 1, Testis-specific Y-encoded-like protein 2, Cutaneous T-cell lymphoma-associated antigen se20-4, Testis-specific Y-encoded-like protein 2, Differentially-expressed nucleolar TGF-beta1 target protein, Testis-specific Y-encoded-like protein 2, Nuclear protein of 79 kDa
NCBI Accession NP_071400
UniProt Q9H2G4
Pathways ER-Nucleus Signaling
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-TSPY-Like 2 (TSPYL2) (AA 380-409), (Center) antibody (ABIN1881953) TSPYL2 Antibody (Center) (ABIN1881953) western blot analysis in MCF-7 cell line lysat...
Background publications Bechtel, Rosenfelder, Duda, Schmidt, Ernst, Wellenreuther, Mehrle, Schuster, Bahr, Blöcker, Heubner, Hoerlein, Michel, Wedler, Köhrer, Ottenwälder, Poustka, Wiemann, Schupp: "The full-ORF clone resource of the German cDNA Consortium." in: BMC genomics, Vol. 8, pp. 399, 2008 (PubMed).

Dephoure, Zhou, Villén, Beausoleil, Bakalarski, Elledge, Gygi: "A quantitative atlas of mitotic phosphorylation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 31, pp. 10762-7, 2008 (PubMed).

Ross, Grafham, Coffey, Scherer, McLay, Muzny, Platzer, Howell, Burrows, Bird, Frankish, Lovell, Howe, Ashurst, Fulton, Sudbrak, Wen, Jones, Hurles, Andrews, Scott, Searle, Ramser, Whittaker, Deadman et al.: "The DNA sequence of the human X chromosome. ..." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Product cited in: Chai, Sarcevic, Mawson, Toh: "SET-related cell division autoantigen-1 (CDA1) arrests cell growth." in: The Journal of biological chemistry, Vol. 276, Issue 36, pp. 33665-74, 2001 (PubMed).

Eichmuller, Usener, Dummer, Stein, Thiel, Schadendorf: "Serological detection of cutaneous T-cell lymphoma-associated antigens." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 2, pp. 629-34, 2001 (PubMed).