anti-IL1RNantibody(Interleukin1ReceptorAntagonist)(AA147-177) 抗体网

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产品名称：anti-IL1RNantibody(Interleukin1ReceptorAntagonist)(AA147-177)
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anti-IL1RNantibody(Interleukin1ReceptorAntagonist)(AA147-177)

详情介绍：

Product Details anti-IL1RN Antibody
Product Details anti-IL1RN Antibody
Immunogen	This IL1RN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-177 amino acids from the C-terminal region of human IL1RN.
Clone	RB18902
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)

Target Details IL1RN
Target Details IL1RN
Alternative Name	IL1RN (IL1RN Antibody Abstract)
Background	The protein is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. A polymorphism of its gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Synonyms: IL1RN, IL1F3, IL1RA, Interleukin-1 receptor antagonist protein, ICIL-1RA, IL1 inhibitor, INN=Anakinra, Flags: Precursor
NCBI Accession	NP_000568, NP_776213, NP_776214, NP_776215
UniProt	P18510
Pathways	NF-kappaB Signaling, Hormone Transport

Application Details
Application Details
Application Notes	WB: 1:1000,FACS: 1:10-50,IF: 1:10-50
Restrictions	For Research Use only

Handling
Handling
Format	Liquid
Concentration	2 mg/mL
Buffer	Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative	Sodium azide
Precaution of Use	WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Images
Images
Supplier Images	IL1RN Antibody (C-term) (ABIN1882098) flow cytometric analysis of HepG2 cells (right ... IL1RN Antibody (C-term) (ABIN1882098) flow cytometric analysis of HepG2 cells (right ... IL1RN Antibody (C-term) (ABIN1882098) flow cytometric analysis of HepG2 cells (right ... Images for product: anti-Interleukin 1 Receptor Antagonist (IL1RN) (AA 147-177), (C-Term) antibody IL1RN Antibody (C-term) (ABIN1882098) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. IL1RN Antibody (C-term) (ABIN1882098) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. IL1RN Antibody (C-term) (ABIN1882098) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

References for anti-IL1RN antibody (ABIN1882098)
References for anti-IL1RN antibody (ABIN1882098)
Product cited in:	Kumar, Kumar, Dixit: "Evidences showing association of interleukin-1B polymorphisms with increased risk of gastric cancer in an Indian population." in: Biochemical and biophysical research communications, Vol. 387, Issue 3, pp. 456-60, 2009 (PubMed).