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  • 产品名称:anti-SynovialApoptosisInhibitor1,Synoviolin(SYVN1)(AA106-138),(N-Term)antibody

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  • 产品厂商:半导体
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简单介绍:
anti-SynovialApoptosisInhibitor1,Synoviolin(SYVN1)(AA106-138),(N-Term)antibody
详情介绍:
Immunogen This HRD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-138 AA from the N-terminal region of human HRD1.
Clone RB15288
Isotype Ig
Predicted Reactivity Mouse (Murine),Xenopus laevis
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name HRD1 (SYVN1 Antibody Abstract)
Background Synonyms: Synovial apoptosis inhibitor 1, E3 ubiquitin-protein ligase synoviolin,KIAA1810, HRD1, SYVN1
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Pathways ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1) (AA 106-138), (N-Term) antibody (ABIN650702) Western blot analysis of HRD1 Antibody (N-term) (ABIN650702) in SK-BR-3 cell line lys...
Product cited in: van den Boomen, Timms, Grice, Stagg, Skødt, Dougan, Nathan, Lehner: "TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 31, pp. 11425-30, 2014 (PubMed).

Wang, Yu, Guo, Zuo, Fisher, Subjeck, Wang: "Enhanced endoplasmic reticulum entry of tumor antigen is crucial for cross-presentation induced by dendritic cell-targeted vaccination." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 12, pp. 6010-21, 2013 (PubMed).

Burr, van den Boomen, Bye, Antrobus, Wiertz, Lehner: "MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 35, pp. 14290-5, 2013 (PubMed).