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  • 产品名称:anti-KCNQ3antibody(PotassiumVoltage-GatedChannel,KQT-LikeSubfamily,Member3)(AA6

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简单介绍:
anti-KCNQ3antibody(PotassiumVoltage-GatedChannel,KQT-LikeSubfamily,Member3)(AA651-679)
详情介绍:
Immunogen This KCNQ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 651-679 AA from the C-terminal region of human KCNQ3.
Clone RB34593
Isotype Ig
Specificity This KCNQ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 650-679 amino acids from the C-terminal region of human KCNQ3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name KCNQ3 (KCNQ3 Antibody Abstract)
Background The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2).
Synonyms: Potassium voltage-gated channel subfamily KQT member 3,KCNQ3,
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure, Neurology
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.45 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3) (AA 651-679), (C-Term) antibody (ABIN658608) KCNQ3 Antibody (C-term) (ABIN658608) western blot analysis in mouse bladder tissue ly...
Background publications Gómez-Posada, Etxeberría, Roura-Ferrer, Areso, Masin, Murrell-Lagnado, Villarroel: "A pore residue of the KCNQ3 potassium M-channel subunit controls surface expression." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 27, pp. 9316-23, 2010 (PubMed).