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  • 产品名称:anti-BRF1antibody(BRF1Homolog,SubunitofRNAPolymeraseIIITranscriptionInitiationF

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简单介绍:
anti-BRF1antibody(BRF1Homolog,SubunitofRNAPolymeraseIIITranscriptionInitiationFactorIIIB(S.Cerevisiae))(AA314-342)
详情介绍:
Immunogen This BRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 AA from the Central region of human BRF1.
Clone RB34097
Isotype Ig
Specificity This BRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-342 amino acids from the Central region of human BRF1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BRF1 (BRF1 Antibody Abstract)
Background This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Two alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. Other transcript variants are possible, but their full-length natures have not been completely characterized. [provided by RefSeq].
Synonyms: Transcription factor IIIB 90 kDa subunit,BRF1,BRF, GTF3B, TAF3B2, TAF3C
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-BRF1 Homolog, Subunit of RNA Polymerase III Transcription Initiation Factor IIIB (S. Cerevisiae) (BRF1) (AA 314-342), (Center) antibody (ABIN658721) BRF1 Antibody (Center) (ABIN658721) western blot analysis in Hela cell line lysates (...
Background publications Haurie, Durrieu-Gaillard, Dumay-Odelot, Da Silva, Rey, Prochazkova, Roeder, Besser, Teichmann: "Two isoforms of human RNA polymerase III with specific functions in cell growth and transformation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 9, pp. 4176-81, 2010 (PubMed).