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  • 产品名称：anti-BEAN1antibody(BrainExpressed,AssociatedwithNEDD4,1)(AA45-73)

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简单介绍：
anti-BEAN1antibody(BrainExpressed,AssociatedwithNEDD4,1)(AA45-73)
详情介绍：
Immunogen This BEAN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 AA from the N-terminal region of human BEAN.
Clone RB32748
Isotype Ig
Specificity This BEAN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human BEAN.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BEAN (BEAN1 Antibody Abstract)
Background The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: Protein BEAN,BEAN,
Research Area Cell Structure, Metabolism, Neurology
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Immunohistochemistry (IHC) image for anti-Brain Expressed, Associated with NEDD4, 1 (BEAN1) (AA 45-73), (N-Term) antibody (ABIN657309) BEAN Antibody (N-term) (ABIN657309) immunohistochemistry analysis in formalin fixed a...
Background publications Sato, Amino, Kobayashi, Asakawa, Ishiguro, Tsunemi, Takahashi, Matsuura, Flanigan, Iwasaki, Ishino, Saito, Murayama, Yoshida, Hashizume, Takahashi, Tsuji, Shimizu, Toda, Ishikawa, Mizusawa: "Spinocerebellar ataxia type 31 is associated with "inserted" penta-nucleotide repeats containing (TGGAA)n." in: American journal of human genetics, Vol. 85, Issue 5, pp. 544-57, 2009 (PubMed).