anti-BCL2/adenovirusE1B19kDaInteractingProtein2(BNIP2)(AA285-316),(C-Term)antib 抗体网

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产品名称：anti-BCL2/adenovirusE1B19kDaInteractingProtein2(BNIP2)(AA285-316),(C-Term)antib
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简单介绍：

anti-BCL2/adenovirusE1B19kDaInteractingProtein2(BNIP2)(AA285-316),(C-Term)antibody

详情介绍：

Product details
Product details
Immunogen	This BNIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-316 AA from the C-terminal region of human BNIP2.
Clone	RB32738
Isotype	Ig
Specificity	This BNIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-435 amino acids from the C-terminal region of human BNIP2.
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.

Target details
Target details
Alternative Name	BNIP2 (BNIP2 Antibody Abstract)
Background	This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. Though the specific function is unknown, it interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. Synonyms: BCL2/adenovirus E1B 19 kDa protein-interacting protein 2,BNIP2,NIP2
Research Area	Apoptosis/Necrosis, Phospho-specific antibodies, Protein Modifications, Cell Structure
Pathways	Regulation of Muscle Cell Differentiation

Application Details
Application Details
Application Notes	WB = 1:1000, IHC (p) = 1:10-50
Restrictions	For Research Use only

Handling
Handling
Format	Liquid
Concentration	0.5 mg/mL
Buffer	PBS with 0.09 % (W/V) sodium azide
Preservative	Sodium azide
Precaution of Use	This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Images
Images
Supplier Images	BNIP2 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).... BNIP2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin ... Images for product: anti-BCL2/adenovirus E1B 19kDa Interacting Protein 2 (BNIP2) (AA 285-316), (C-Term) antibody BNIP2 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the BNIP2 antibody detected the BNIP2 protein (arrow). BNIP2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BNIP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

References
References
Background publications	Scott, Bowles, Wilson, Meade, Low, Davison, Blair, Cook: "Identification of the BCL2/adenovirus E1B-19K protein-interacting protein 2 (BNIP-2) as a granzyme B target during human natural killer cell-mediated killing." in: The Biochemical journal, Vol. 431, Issue 3, pp. 423-31, 2010 (PubMed). Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed). Valencia, Cotten, Liu: "Cleavage of BNIP-2 and BNIP-XL by caspases." in: Biochemical and biophysical research communications, Vol. 364, Issue 3, pp. 495-501, 2007 (PubMed). Shang, Zhou, Low: "Concerted regulation of cell dynamics by BNIP-2 and Cdc42GAP homology/Sec14p-like, proline-rich, and GTPase-activating protein domains of a novel Rho GTPase-activating protein, BPGAP1." in: The Journal of biological chemistry, Vol. 278, Issue 46, pp. 45903-14, 2003 (PubMed).