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  • 产品名称：anti-GDF5antibody(GrowthDifferentiationFactor5)(AA343-371)

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简单介绍：
anti-GDF5antibody(GrowthDifferentiationFactor5)(AA343-371)
详情介绍：
Immunogen This GDF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-371 AA from the C-terminal region of human GDF5.
Clone RB31942
Isotype Ig
Specificity This GDF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-379 amino acids from the C-terminal region of human GDF5.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name GDF5 (GDF5 Antibody Abstract)
Background The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and ***** tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type, brachydactyly, type C, and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.
Synonyms: GDF5,Growth/differentiation factor 5,CDMP1
Molecular Weight 55411 DA
Gene ID 8200
NCBI Accession NP_000548
UniProt P43026
Research Area Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Growth Differentiation Factor 5 (GDF5) (AA 343-371), (C-Term) antibody (ABIN655977) GDF5 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/la...
Immunohistochemistry (IHC) image for anti-Growth Differentiation Factor 5 (GDF5) (AA 343-371), (C-Term) antibody (ABIN655977) GDF5 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin e...