anti-TSC2antibody(TuberousSclerosis2)(pThr1373) 抗体网

产品详情

所在位置: 首页> 产品目录> 一抗>

查看大图

产品名称：anti-TSC2antibody(TuberousSclerosis2)(pThr1373)
产品型号：
产品厂商：半导体
产品文档：

你添加了1件商品查看购物车

简单介绍：

anti-TSC2antibody(TuberousSclerosis2)(pThr1373)

详情介绍：

Product Details anti-TSC2 Antibody
Product Details anti-TSC2 Antibody
Immunogen	This rat TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1373 of rat TSC2.
Clone	RB41276
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Target Details TSC2
Target Details TSC2
Alternative Name	TSC2 (TSC2 Antibody Abstract)
Background	Acts as a tumor suppressor, may play a role in cell cycle regulation, acute phase response, and negative regulation of cell proliferation [RGD]. Synonyms: Tsc2, Tuberin, Tuberous sclerosis 2 protein homolog
NCBI Accession	NP_036812
UniProt	P49816
Pathways	RTK Signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus

Application Details
Application Details
Application Notes	DB: 1:500
Restrictions	For Research Use only

Handling
Handling
Format	Liquid
Concentration	0.38 mg/mL
Buffer	Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative	Sodium azide
Precaution of Use	WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Images
Images
Supplier Images	Dot blot analysis of rat TSC2 Antibody (Phospho T1373) Phospho-specific Pab (ABIN1881... Dot blot analysis of rat TSC2 Antibody (Phospho T1373) Phospho-specific Pab (ABIN1881935) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6 µg per mL. Dot blot analysis of rat TSC2 Antibody (Phospho T1373) Phospho-specific Pab (ABIN1881935) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6 µg per mL.

References for anti-TSC2 antibody (ABIN1881935)
References for anti-TSC2 antibody (ABIN1881935)
Product cited in:	Larson, Liu, Stevens, Li, Li, Evers, Gao: "Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24987-98, 2010 (PubMed). Di Nardo, Kramvis, Cho, Sadowski, Meikle, Kwiatkowski, Sahin: "Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 18, pp. 5926-37, 2009 (PubMed). Shiono, Kobayashi, Takahashi, Sun, Abe, Zhang, Wang, Piao, Takagi, Mineki, Taka, Tada, Sonobe, Momose, Ueda, Hino: "The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition." in: Oncogene, Vol. 27, Issue 52, pp. 6690-7, 2008 (PubMed).