anti-PFKFB2antibody(6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase2)(AA1-3 抗体网

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产品名称：anti-PFKFB2antibody(6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase2)(AA1-3
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简单介绍：

anti-PFKFB2antibody(6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase2)(AA1-30)

详情介绍：

Product Details anti-PFKFB2 Antibody
Product Details anti-PFKFB2 Antibody
Immunogen	This PFKFB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human PFKFB2.
Clone	RB4031-4032
Isotype	Ig
Specificity	This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PFKFB2.
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Target Details PFKFB2
Target Details PFKFB2
Alternative Name	PFKFB2 (PFKFB2 Antibody Abstract)
UniProt	O60825
Research Area	Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Pathways	PI3K-Akt Signaling, Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process

Application Details
Application Details
Application Notes	WB = 1:1000, IHC (p) = 1:50-100
Restrictions	For Research Use only

Handling
Handling
Format	Liquid
Concentration	2 mg/mL
Buffer	PBS with 0.09 % (W/V) sodium azide
Preservative	Sodium azide
Precaution of Use	This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage	4 °C/-20 °C
Storage Comment	Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.
Expiry Date	6 months

Images
Images
Supplier Images	Western blot analysis of anti-PFKFB2 Pab (ABIN392769) in mouse kidney tissue lysate (... Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant... Images for product: anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) (AA 1-30), (N-Term) antibody Western blot analysis of anti-PFKFB2 Pab (ABIN392769) in mouse kidney tissue lysate (35 μg/lane). PFKFB2(arrow) was detected using the purified polyclonal antibody (1:50 dilution) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma

References for anti-PFKFB2 antibody (ABIN392769)
References for anti-PFKFB2 antibody (ABIN392769)
Product cited in:	Xia, Hong, Ye, Wang, Chen, Liu: "Label-free quantitative proteomic analysis of right ventricular remodeling in infant Tetralogy of Fallot patients." in: Journal of proteomics, Vol. 84, pp. 78-91, 2013 (PubMed). Carlet, Janjetovic, Rainer, Schmidt, Panzer-Grümayer, Mann, Prelog, Meister, Ploner, Kofler: "Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells." in: BMC cancer, Vol. 10, pp. 638, 2010 (PubMed). Yalcin, Clem, Simmons, Lane, Nelson, Clem, Brock, Siow, Wattenberg, Telang, Chesney: "Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases." in: The Journal of biological chemistry, Vol. 284, Issue 36, pp. 24223-32, 2009 (PubMed).