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  • 产品名称：anti-Kallikrein14antibody(KLK14)(AA15-44)

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简单介绍：
anti-Kallikrein14antibody(KLK14)(AA15-44)
详情介绍：
Immunogen This KLK14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 AA from the N-terminal region of human KLK14.
Clone RB34521
Isotype Ig
Specificity This KLK14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-44 amino acids from the N-terminal region of human KLK14.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name KLK14 (KLK14 Antibody Abstract)
Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. An additional transcript variant has been described but its full length nature has not been determined.
Synonyms: Kallikrein-14,KLK14,KLKL6
Research Area Cell Signaling, Protein Modifications, Metabolism, Cell Structure
Pathways Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.3 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-Kallikrein 14 (KLK14) (AA 15-44), (N-Term) antibody (ABIN658744) KLK14 Antibody (N-term) (ABIN658744) western blot analysis in NCI-H292 cell line lysa...
Background publications Lai, Myers, Lawrence, Odorico, Clements: "Direct progesterone receptor and indirect androgen receptor interactions with the kallikrein-related peptidase 4 gene promoter in breast and prostate cancer." in: Molecular cancer research : MCR, Vol. 7, Issue 1, pp. 129-41, 2009 (PubMed).

Paliouras, Diamandis: "Androgens act synergistically to enhance estrogen-induced upregulation of human tissue kallikreins 10, 11, and 14 in breast cancer cells via a membrane bound androgen receptor." in: Molecular oncology, Vol. 1, Issue 4, pp. 413-24, 2009 (PubMed).