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Alternative Name
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P2RY1 (P2RY1 Antibody Abstract)
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Background
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The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq].
Synonyms: P2Y purinoceptor 1,P2RY1,
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Molecular Weight
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42072 DA
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Gene ID
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5028
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NCBI Accession
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NP_002554
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UniProt
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P47900
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Research Area
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Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
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Pathways
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Regulation of Carbohydrate Metabolic Process, Feeding Behaviour
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