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  • 产品名称：anti-Asparagine-LinkedGlycosylation11,alpha-1,2-MannosyltransferaseHomolog(Yeas

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简单介绍：
anti-Asparagine-LinkedGlycosylation11,alpha-1,2-MannosyltransferaseHomolog(Yeast)(ALG11)(AA344-373),(C-Term)antibody
详情介绍：
Immunogen This ALG11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 AA from the C-terminal region of human ALG11.
Clone RB35165
Isotype Ig
Specificity This ALG11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-373 amino acids from the C-terminal region of human ALG11.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ALG11 (ALG11 Antibody Abstract)
Background This gene encodes a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which is localized to the cytosolic side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip (CDGIP). This gene overlaps but is distinct from the UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) gene. A pseudogene of the GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase has been identified on chromosome 19.
Synonyms: Asparagine-linked glycosylation protein 11 homolog,ALG11,GT8
Research Area Protein Modifications, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.46 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-Asparagine-Linked Glycosylation 11, alpha-1,2-Mannosyltransferase Homolog (Yeast) (ALG11) (AA 344-373), (C-Term) antibody (ABIN658801) ALG11 Antibody (C-term) (ABIN658801) western blot analysis in HepG2 cell line lysates...
Background publications Rind, Schmeiser, Thiel, Absmanner, Lübbehusen, Hocks, Apeshiotis, Wilichowski, Lehle, Körner: "A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip." in: Human molecular genetics, Vol. 19, Issue 8, pp. 1413-24, 2010 (PubMed).