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  • 产品名称：anti-ACSS2antibody(Acyl-CoASynthetaseShort-ChainFamilyMember2)(AA261-290)

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简单介绍：
anti-ACSS2antibody(Acyl-CoASynthetaseShort-ChainFamilyMember2)(AA261-290)
详情介绍：
Immunogen This ACSS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-290 AA from the Central region of human ACSS2.
Clone RB33058
Isotype Ig
Specificity This ACSS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-290 amino acids from the Central region of human ACSS2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ACSS2 (ACSS2 Antibody Abstract)
Background This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Synonyms: Acetyl-coenzyme A synthetase, cytoplasmic,ACSS2,ACAS2
Research Area Signaling, Phospho-specific antibodies, Protein Modifications, Chromatin, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-Acyl-CoA Synthetase Short-Chain Family Member 2 (ACSS2) (AA 261-290), (Center) antibody (ABIN657155) ACSS2 Antibody (Center) (ABIN657155) western blot analysis in HepG2 cell line lysates...
Background publications Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).