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产品名称:anti-RNF43antibody(RingFingerProtein43)(AA543-572)
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产品厂商:半导体
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简单介绍:
anti-RNF43antibody(RingFingerProtein43)(AA543-572)
详情介绍:
Product Details anti-RNF43
Antibody
Product Details anti-RNF43 Antibody
Immunogen
This RNF43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-572 AA from the C-terminal region of human RNF43.
Clone
RB32930
Isotype
Ig
Specificity
This RNF43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 542-572 amino acids from the C-terminal region of human RNF43.
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Target Details RNF43
Target Details RNF43
Alternative Name
RNF43 (RNF43 Antibody Abstract)
Background
RNF43 is a HAP95 (AKAP8L, MIM 609475) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer (Yagyu et al., 2004 [PubMed 15492824], Sugiura et al., 2008 [PubMed 18313049]).
Synonyms: RING finger protein 43,RNF43,
Research Area
Ubiquitin-related antibodies, Cell Signaling, Protein Modifications, Cell Structure
Application Details
Application Details
Application Notes
WB = 1:1000, IHC (p) = 1:10-50
Restrictions
For Research Use only
Handling
Handling
Format
Liquid
Concentration
0.5 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Images
Images
Supplier Images
RNF43 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).T...
RNF43 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin ...
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Images for product: anti-Ring Finger Protein 43 (RNF43) (AA 543-572), (C-Term) antibody
RNF43 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the RNF43 antibody detected the RNF43 protein (arrow).
RNF43 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RNF43 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
References for anti-RNF43 antibody (ABIN657128)
References for anti-RNF43 antibody (ABIN657128)
Background publications
Yagyu, Furukawa, Lin, Shimokawa, Yamamura, Nakamura: "A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer."
in:
International journal of oncology
, Vol. 25, Issue 5, pp. 1343-8, 2004 (PubMed).