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  • 产品名称:anti-RAB8Aantibody(RAB8A,MemberRASOncogeneFamily)

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简单介绍:
anti-RAB8Aantibody(RAB8A,MemberRASOncogeneFamily)
详情介绍:
Immunogen This RAB8A antibody is generated from rabbits immunized with human RAB8A recombinant protein.
Clone RB22933
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name RAB8A (RAB8A Antibody Abstract)
Background The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. Anessential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. RAB8A is a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome.

Synonyms: RAB8A, MEL, RAB8, Ras-related protein Rab-8A, Oncogene c-mel
NCBI Accession NP_005361
UniProt P61006
Research Area Signaling
Pathways M Phase, Regulation of long-term Neuronal Synaptic Plasticity
Application Notes WB: 1:1000,IHC (p): 1:50-100,FACS: 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Flow Cytometry (FACS) image for anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibody (ABIN1881723) RAB8A Antibody (ABIN1881723) flow cytometric analysis of Hela cells (right histogram)...
Immunohistochemistry (IHC) image for anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibody (ABIN1881723) RAB8A Antibody (ABIN1881723) flow cytometric analysis of Hela cells (right histogram)...
Western Blotting (WB) image for anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibody (ABIN1881723) RAB8A Antibody (ABIN1881723) flow cytometric analysis of Hela cells (right histogram)...
Product cited in: Rosas, Gabler, Vantman, Romero, Vega: "Levels of Rabs and WAVE family proteins associated with translocation of GLUT4 to the cell surface in endometria from hyperinsulinemic PCOS women." in: Human reproduction (Oxford, England), Vol. 25, Issue 11, pp. 2870-7, 2010 (PubMed).

Kato, Sekine, Oh, Kim, Umezawa, Abe, Yokoyama-Kobayashi, Aoki: "Construction of a human full-length cDNA bank." in: Gene, Vol. 150, Issue 2, pp. 243-50, 1995 (PubMed).