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  • 产品名称：anti-RASD1antibody(RAS,Dexamethasone-Induced1)(AA248-277)

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简单介绍：
anti-RASD1antibody(RAS,Dexamethasone-Induced1)(AA248-277)
详情介绍：
Immunogen This RASD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-277 AA from the C-terminal region of human RASD1.
Clone RB31294
Isotype Ig
Specificity This RASD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-278 amino acids from the C-terminal region of human RASD1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name RASD1 (RASD1 Antibody Abstract)
Background This gene encodes a Ras-related protein that is stimulated by dexamethasone. The exact function of this gene is unknown, but it may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. In addition, studies of a similar rat protein suggest that it functions as as a novel physiologic nitric oxide (NO) effector. The gene product belongs to the Ras superfamily of small GTPases.
Synonyms: Dexamethasone-induced Ras-related protein 1,RASD1,AGS1, DEXRAS1
Research Area Signaling, Protein Modifications, Cell Structure, Chromatin
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.28 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-RAS, Dexamethasone-Induced 1 (RASD1) (AA 248-277), (C-Term) antibody (ABIN657026) RASD1 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/la...
Immunohistochemistry (IHC) image for anti-RAS, Dexamethasone-Induced 1 (RASD1) (AA 248-277), (C-Term) antibody (ABIN657026) RASD1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin ...
Background publications Nojima, Maruyama, Yasui, Suzuki, Maruyama, Tarasawa, Sasaki, Asaoku, Sakai, Hayashi, Mori, Imai, Tokino, Ishida, Toyota, Shinomura: "Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 13, pp. 4356-64, 2009 (PubMed).

Lau, Chan, Perkinton, Tudor, Chang, Chan, McLoughlin, Miller: "Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34728-37, 2008 (PubMed).