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  • 产品名称：anti-TTPAantibody(Tocopherol(Alpha)TransferProtein)(AA82-108)

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简单介绍：
anti-TTPAantibody(Tocopherol(Alpha)TransferProtein)(AA82-108)
详情介绍：
Immunogen This TTPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-108 amino acids from the Central region of human TTPA.
Clone RB42171
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name TTPA (TTPA Antibody Abstract)
Background This gene encodes a soluble protein that binds alpha-trocopherol, a form of vitamin E, with high selectivity and affinity. This protein plays an important role in regulating vitamin E levels in the body by transporting vitamin E between membrane vesicles and facilitating the secretion of vitamin E from hepatocytes to circulating lipoproteins. Mutations in this gene cause hereditary vitamin E deficiency (ataxia with vitamin E deficiency, AVED) and retinitis pigmentosa.

Synonyms: TTPA, TPP1, Alpha-tocopherol transfer protein
NCBI Accession NP_000361
UniProt P49638
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Tocopherol (Alpha) Transfer Protein (TTPA) (AA 82-108), (Center) antibody (ABIN1881957) TTPA Antibody (Center) (ABIN1881957) western blot analysis in CEM cell line lysates (...
Product cited in: Wirth, Poletti, Aeschlimann, Yakandawala, Drosse, Osorio, Tohge, Fernie, Günther, Gruissem, Sautter: "Rice endosperm iron biofortification by targeted and synergistic action of nicotianamine synthase and ferritin." in: Plant biotechnology journal, Vol. 7, Issue 7, pp. 631-44, 2009 (PubMed).

Wright, Peters, Gunter, Moore, Lawson, Yeager, Weinstein, Snyder, Virtamo, Albanes: "Association of variants in two vitamin e transport genes with circulating vitamin e concentrations and prostate cancer risk." in: Cancer research, Vol. 69, Issue 4, pp. 1429-38, 2009 (PubMed).

Fusco, Frattini, Pisani, Gellera, Della Giustina: "Isolated vitamin E deficiency mimicking distal hereditary motor neuropathy in a 13-year-old boy." in: Journal of child neurology, Vol. 23, Issue 11, pp. 1328-30, 2008 (PubMed).

Rotzoll, Scherling, Etzl, Stepan, Horn, Pöschl: "Immunohistochemical localization of alpha-tocopherol transfer protein and lipoperoxidation products in human first-trimester and term placenta." in: European journal of obstetrics, gynecology, and reproductive biology, Vol. 140, Issue 2, pp. 183-91, 2008 (PubMed).

Kara, Uzümcü, Uyguner, Rosti, Koçbaş, Ozmen, Kayserili: "Ataxia with vitamin E deficiency associated with deafness." in: The Turkish journal of pediatrics, Vol. 50, Issue 5, pp. 471-5, 2008 (PubMed).